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Custom Manufacturing
Syngene's custom manufacturing unit supplies customized molecules to several highly reputed research units in the USA and Europe. We have acquired technical capabilities in scaling up complex chemical and biochemical processes. Our cGMP accredited pilot plant (glass-lined and stainless steel chemical reactors: 20l -1500l) is fully equipped to develop intermediates and final products.
Synthesis of organic molecules involves diverse chemistry. Some of the reactions carried out by our custom synthesis unit at gram to kilogram scale include:
Lab Scale
Ozonolysis
Cyanations
Diel-Alder Chemistry
Evans Chemistry
CBS Reductions
Carbonylations
LAH
BMS
Choloroformates
Azides
Metal Amides
Diazomethane
Carbon disulfide
Thiophosgene
Phosphines
Pilot Plant Scale
Lithiations
Bromination
Oxidations
Nitrations
Resolutions
Suzuki Couplings
DIBAL-H
Bromine
PCl5
POCl3
KMnO4
Pd(PPh3)4 etc.
Plant Scale
Lithiations
Alkylations
Reduction
Alkyl Lithiums
Sodium Hydride
Raney Nickel
Borohydrides
Pilot Plant Capabilities:
Our pilot plant facilities are equipped with both glass lined and stainless steel reactors (maximum capacity of 1500L) which can handle temperatures ranging from +1200C to -1000C. We have separate solvent storage and hydrogenation facilities for pilot scale production. We also have a state-of-the-art solvent recovery system for distilling different solvents.
In addition, our large scale facility also includes an underground solvent storage facility and specialized rectors for hydrogenation and crystallization purpose to suit most client needs.
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